Guinea pig model for Staphylococcus aureus native valve endocarditis.
نویسندگان
چکیده
We present a new experimental model of Staphylococcus aureus infective endocarditis in guinea pigs. Permanent aortic valve damage was produced by electrocoagulation after catheterization of the right carotid artery, which allowed avoidance of the intracardiac catheter to produce cardiac vegetations. Our model closely mimics pathological mechanisms of native valve endocarditis.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 41 8 شماره
صفحات -
تاریخ انتشار 1997